Free Grade 12 Biology Worksheets with Answers

Grade 12 Cell Transport & Homeostasis

HS-LS1-3

Diffusion, osmosis and active transport, and how cells keep stable conditions.

e.g. A cell is placed in very salty water. What happens to it?

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Grade 12 Photosynthesis & Respiration

HS-LS1-5

Photosynthesis and cellular respiration: their inputs, outputs and where each takes place in the cell.

e.g. What energy-carrying molecule does cellular respiration produce?

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Grade 12 Mitosis & Meiosis

HS-LS1-4

The stages of mitosis and meiosis and how the two kinds of cell division differ.

e.g. During which phase of mitosis are sister chromatids pulled apart?

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Grade 12 DNA, RNA & Protein Synthesis

HS-LS1-1

DNA structure, base pairing, transcription and translation — including writing complementary strands.

e.g. Why is DNA replication called semi-conservative?

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Grade 12 Punnett Squares & Crosses

HS-LS3-3

Predicting offspring with Punnett squares and working out genotype and phenotype ratios.

e.g. Cross Tt × tt. What is the expected ratio of dominant to recessive phenotypes?

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Grade 12 Natural Selection & Adaptation

HS-LS4-4

Variation, mutation and natural selection, and how populations change over generations.

e.g. What is natural selection?

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Grade 12 Classification & Taxonomy

HS-LS4-1

Domains, kingdoms and scientific names, and how organisms are classified.

e.g. Why do scientists use DNA to classify organisms?

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Grade 12 Population Ecology

HS-LS2-1

Population growth, limiting factors, carrying capacity and biodiversity.

e.g. Exponential growth looks like what shape on a graph?

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Grade 12 Biomes & Symbiosis

HS-LS2-6

Biomes and the relationships between species: mutualism, commensalism, parasitism and predation.

e.g. What is it called when two organisms live closely together and both benefit?

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Grade 12 Human Impact & Sustainability

HS-ESS3-3

How human activity affects Earth's systems and how to use resources sustainably.

e.g. How can cities reduce flooding?

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Grade 12 Advanced Biology (Mixed)

A mixed set on photosynthesis, cellular respiration, mitosis and meiosis.

e.g. What sugar is made during photosynthesis?

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Grade 12 Genetics Basics (Mixed)

HS-LS3-2

A mixed set on genetics vocabulary and Punnett square crosses.

e.g. Cross YY × YY. What is the expected ratio of dominant to recessive phenotypes?

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Grade 12 Challenge: Think Like a Scientist

Challenge

Surprising questions and thought experiments that test real scientific reasoning.

e.g. If Earth stopped spinning, how long would one day (sunrise to sunrise) be?

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